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One-stop reference on homogeneous catalysis, from general concepts through detailed examples and industrial applications Accessible and richly illustrated, Applied Homogeneous Catalysis provides a concise overview of the broad field of homogeneous transition metal catalysis and its applications in the chemical industry. This newly revised and updated second edition puts special emphasis on green chemistry, sustainable resources, and processes. The book is divided into five parts. Part I presents the basics of transition metal catalysis. Part II focuses on process engineering aspects. Part III provides details of the most important catalytic reactions. Part IV describes catalytic conversions closely related to classical homogeneous transition metal catalysis, such as nano-, electro-, photo- and organocatalysis. Part V covers new feedstocks and other topics, concluding with an outlook on future challenges of homogeneous catalysis. The book contains numerous mechanistic details, technical information, and illustrative examples. The chapters are enlivened by various excursions that relate the content to everyday life or introduce important personalities. Didactically, the book is completed with learning objectives and take-home messages for each chapter, as well as more than 400 questions and answers for self-testing. Written by a team of internationally renowned experts in the field, with a wealth of experience in industry and teaching, Applied Homogeneous Catalysis includes information on: Economic importance of industrial homogeneously-catalyzed reactions and basics of organometallic chemistry, including types of bonds, elemental steps, and mechanisms Common approaches for separating the homogeneous catalyst from the products after the reaction and using combinatorial chemistry and high throughput screening to achieve optimal results Activating “inactive” molecules such as carbon dioxide and nitrogen, and harnessing homogeneous catalysis for feedstock diversification by recycling polymers or using renewables. Providing expansive coverage of the subject, Applied Homogeneous Catalysis is an essential guide for researchers and professionals in the pharmaceutical, polymer, and fine and bulk chemicals industries working on catalysis or entering the field, as well as for Master’s and PhD students in organic chemistry, chemical engineering, and related fields. Preface of the Authors xvii Introduction: Adhering to the Principles of Green Chemistry: How Does Homogeneous Catalysis Contribute? Chemical Basics Definition, Variants and Examples: What Actually Is Catalysis? A Brief History: Homogeneous Transition Metal Catalysis: A Young Science Industrial Homogeneous Catalysis: What Is the Economic Importance? Definition of Important Terms: X, Y, S, STY, TON, TOF and more… Basics of Organometallic Chemistry: Bonds, Elementary Steps and Mechanisms Transition Metal Compounds: The ‘Captains’ of Homogeneous Catalysis Ligands: The ‘Helmsmen’ of Homogeneous Catalysis Solvents in Homogeneous Catalysis: The Reaction Medium Enantioselective Catalysis: The “Special Case” Thermodynamics of Homogeneous Catalysis: When Does a Chemical Reaction Run? Kinetics of Homogeneous Catalysis: How Does the Reaction Proceed? Overview of Spectroscopic Methods: Can We See into Homogeneous Catalysis? Process Engineering Fundamentals Reactor Types: Where Homogeneous Catalysis Actually Occurs Overview of Catalyst Separation Techniques: How Catalyst and Product Go Their Separate Ways After the Reaction Catalyst Separation by Membranes: A Barrier Between Products and Catalysts Immobilisation on Solid Supports: From Homogeneity to Heterogeneity Liquid–Liquid Multiphase Systems: The Smart Approach to Catalyst Separation Switchable Multiphase Systems: Triggering Separation of Homogeneous Mixtures Optimisation Strategies: Combinatorial Synthesis, Design of Experiments and High-Throughput Screening Process Development in Miniplants: From Laboratory to Production Homogeneously Catalysed Reaction Types Carbonylation: The Versatile Insertions of Carbon Monoxide Oligomerisation and Cyclooligomerisation: The Conversion of Unsaturated Aliphatics into Short Chains or Medium-Sized Rings Metathesis: A ‘Change-Your-Partners’ Dance Polymerisation: The Purposeful Assembly of Macromolecules Telomerisation: The Construction of Functionalised Aliphatic Chains Carbon–Carbon Coupling Reactions: Quite a lot of Name Reactions Hydrogenation: C––H Bond Formation Oxidation: C––O Bond Formation Amination and Hydroamination: C––N Bond Formation Hydrofunctionalisation: Formation of Further C––X Bonds Isomerisation and Rearrangement: Migration of Double Bonds and Rearrangement of the Carbon Backbone Associated Catalysis Tandem Reactions: Multiple Synthesis Steps in One Pot Nanocatalysis: A Balancing Act Between Homogeneous and Heterogeneous Catalysis Electrocatalysis: Catalysis with Electrons Organocatalysis: Homogeneous Catalysis only with Organic Compounds New Resources Alkane Activation: Acquisition of New Feedstocks Reactions with Carbon Dioxide: Activating an ‘Inactive’ Molecule Nitrogen Activation: Reaching for the Air Recycling of Polymers: The Use of Waste Homogeneous Catalysis with Renewables: Using Nature’s Treasures Future Challenges of Homogeneous Catalysis: What the Crystal Ball Might Tell You Epilogue Answers to the Exercise Questions Excursions Photo Credits Index